Endocrine Abstracts

Introduction: Noonan syndrome (NS) is an autosomal dominant disorder or may occur on a sporadic basis, characterized by short stature, typical face dysmorphology and congenital heart defects. NS is a clinical diagnosis. Establishing the diagnosis can be very difficult, especially in adulthood. There is a great variability in expression and the phenotype become less pronounced with increasing age. The scoring system of Van der Burgt et al. has been devised to help the di...

Background: Secondary adrenal insufficiency is a common complication of transsphenoidal hypophysectomy (TSS) for pituitary adenoma. It is therefore imperative to rapidly and accurately identify patients requiring glucocorticoid replacement, thus minimising risks of adrenal insufficiency or unnecessary glucocorticoid exposure. The gold-standard test of HPA axis reserve, the insulin tolerance test (ITT), cannot be performed safely until after post-operative recovery. Nine am cor...

Background: Low muscle mass and obesity in surgical patients are a prevalent phenomenom that is associated with outcomes such as higher surgical an clinical complications and poor. However, the significance of sarcopenia and sarcopenic obesity in the liver transplantation (LT) population remains unclear. The purpose of this study is to investigate the impact of low skeletal muscle mass, muscle quality and sarcopenic obesity on patients awaiting LT.Method...